CANDIDOSES VAGINALES A CASABLANCA: IMPLICATION DES ESPECES NON ALBICANS ET PARTICULARITES ETIOLOGIQUES

Abstract

The purpose of this study was to determine the prevalence of vaginal candidiasis in Moroccan women, to analyze their clinical and mycological characteristics, as well as to clarify the importance of etiologic diagnosis and the influence of non-albicans species in the occurrence of infection and risk factors. Material and method.This is a prospective study including 697 vaginal specimens from2006 to 2009. The isolates were obtained from Moroccan women attending the center of medical biology at the Pasteur Institute of Casablancato perform the Pap test.An information sheet has been completed for every participant. For each sample, direct examination and culture medium with Sabouraud-chloramphenicol were performed. The yeast identification was carried out by a morphological, physiological tests and PCR. Results.The direct examination in the fresh state was positive in 13,48% of cases, while the culture indicated that 20,65% were positives. Candidaalbicans was the most isolated specie among the five Candida species identified (47,22%), followed by C. glabrata (34,21%), C. tropicalis (3,94%), C. parapsilosis (3,94%) and C.dubliniensis (2,63%). The most affected age group was [28-38] years. The presence of vaginal discharge was the most common sign (50.7%), followed by vaginal inflammation (29.16%), vulvar pruritus (23.61%). Several risk factors were associated with the infection: age, pregnancy, abortions and submission to the cesarean. Conclusion.Vaginal candidiasis is an important cause of morbidity in women of reproductive age; C. albicansis the most common causative agent but a significant increase in the frequency of non-albicans species was also demonstrated.